Hemophilia A symptoms

Dive into the details of hemophilia A signs and symptoms, which can all vary depending on the individual.

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Signs and symptoms of hemophilia A

Hemophilia A symptoms can include1,2:

Signs and symptoms of hemophilia A vary with the individual. If your clotting-factor level is mildly reduced, you might bleed only after serious trauma.

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Excessive bleeding or bruising in the joints, muscles, or soft tissue

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Pain, swelling, or tightness in joints

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Bleeding of the mouth and gums and bleeding after losing a tooth

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Bleeding from an injury or medical procedure

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Bleeding in the head of an infant after a difficult delivery

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Blood in the urine or stool

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Frequent and hard-to-stop nosebleeds

If your clotting-factor level is greatly reduced, though, you can bleed easily from a small cut, or even for seemingly no reason. A bump on the head can even cause bleeding into the brain for some people. This is rare, but it's one of the most serious complications that can occur.

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Mild, moderate, or severe hemophilia A3

A person can have mild, moderate, or severe hemophilia A. It depends on how much working clotting factor is in the blood. The standard factor level is 100%. You can have a factor level between 50% and 150% and still be considered normal. In a person with hemophilia A, the clotting factor level is much lower than the standard.

Mild Hemophilia A

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Mild hemophilia A
6% to 49% working factor VIII

  • Bleeding only after serious: trauma, injury, surgery
  • First episode may not occur until adulthood
  • Women may experience heavy menstrual bleeding, hemorrhage during childbirth

Moderate Hemophilia A

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Moderate hemophilia A
1% to 5% factor level

  • Bleeding after injuries or trauma

Severe Hemophilia A

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Severe hemophilia A
Less than 1% factor level

  • Bleeding after injuries and spontaneously with no obvious cause (often into muscles and joints)
  • Boys with severe hemophilia A are often diagnosed after circumcision

Keep exploring

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What causes hemophilia A?

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Doctor discussing treatment options with a patient during an appointment.

Treatment options for hemophilia A

LEARN MORE
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What are the severity levels of hemophilia A?

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  1. Srivastava A, Santagostino E, Dougall A, et al. WFH Guidelines for the Management of Hemophilia, 3rd edition. Haemophilia. 2020:26(suppl 6):1-158. https://doi.org/10.1111/hae.14046
  2. Mayo Clinic. Hemophilia. https://www.mayoclinic.org/diseases-conditions/hemophilia/symptoms-causes/syc-20373327. Accessed February 12, 2023.
  3. National Hemophilia Foundation. Hemophilia A. https://www.hemophilia.org/Bleeding-Disorders/Types-of-Bleeding-Disorders/Hemophilia-A. Accessed February 12, 2023.